Dr. Heidi Huttunen-HennellyAssociate Professor | Faculty of Science
Email: hhuttunen@tru.ca
Phone: 1-250-377-6063
Interests
Spending time with family and friends, watching WolfPack varsity games, sports, traveling, and gardening.
Research Interests
Using the de novo approach to design antimicrobial peptides (AMPs)
Studying AMP structure-activity relationships
Developing novel methods to investigate AMP mechanism of action
Education
BSc (University of British Columbia, 2000)
PhD (University of British Columbia, 2006)
Publications
Matheson, S.; Cheeptham, N.; Huttunen-Hennelly, H.E.K. Investigating the Effects of Hydrophobicity and
Charge on the Therapeutic Ability of the Antimicrobial Histatin 8 Peptide for Potential Use in Oral
Applications, International Journal of Biology. 2013, 5, 85-91.
Azad, M.A.; Huttunen-Hennelly, H.E.K.; Ross Friedman, C. Bioactivity and the First TEM Immunogold
Studies of Short de novo Designed Antimicrobial Peptides, Antimicrob. Agents Ch. 2011, 55,
2137-2145.
Jones, D.S.A.; Huttunen-Hennelly, H.E.K.; Donkor, K.K. The Design and Synthesis of Alanine-Based
Indolicidin Derivatives with Identical Physiochemical Properties, and their Separation Using Capillary
Electrophoresis, Anal. Bioanal. Chem. 2010, 398, 3073-3079.
Podorieszach, A.P.; Huttunen-Hennelly, H.E.K. The Effects of Tryptophan and Hydrophobicity on the
Structure and Bioactivity of Novel Indolicidin Derivatives with Promising Pharmaceutical Potential, Org.
Biomol. Chem. 2010, 8, 1679-1687.
Huttunen-Hennelly, H.E.K. An Investigation into the N- and C-Capping Effects of Glycine in
Cavitand-Based Four-Helix Bundle Proteins, Bioorg. Chem. 2010, 38, 98-107.
Huttunen-Hennelly, H.E.K.; Sherman, J.C. An Investigation into the Native-Like Properties of De Novo
Designed Cavitand-Based Four-Helix Bundle Proteins, Pept. Sci. 2008, 1, 37-50.
Huttunen-Hennelly, H.E.K.; Sherman, J.C. The Design, Synthesis, and Characterization of the First
Cavitand-Based De Novo Hetero-Template-Assembled Synthetic Proteins (Hetero-TASPs), Org. Biomol. Chem.
2007, 5, 3637-3650.
Scott, W.R.P.; Seo, E.; Huttunen, H.; Wallhorn, D.; Sherman, J.C.; Straus, S.K. Characterization of de
Novo Four-Helix Bundles by Molecular Dynamics Simulations, Proteins: Struc. Func. Bioinfor. 2006, 64,
719-729.
Courses Taught
Chem 120 (Fundaments of Chemistry 2)
Chem 121 (Principles of Chemistry 2)
Chem 121/125L (Principles of Chemistry Lab)
Chem 1500 (Chemical Bonding and Organic Chemistry)
Chem 2120 (Organic Chemistry 1)
Chem 2220 (Organic Chemistry 2)
Chem 2250 (Fundamentals of Physical Chemistry)
Chem 2250L (Fundamentals of Physical Chemistry Lab)
Chem 3220 (Advanced Organic Chemistry)
Chem 3230 (Organic Spectroscopy)
Chem 3240 (Organic Chemistry Laboratory)
Chem 4450 (Advanced Chemical Biology Lab)
