CHEM 2223: Organic Chemistry II

Students continue their study of organic chemistry by discussing aromatic compounds, aldehydes and ketones, carboxylic acids and their derivatives, and organic nitrogen compounds. Synthesis using carbanion and enolate ion methods are emphasized. Students also explore the chemistry of various organic compounds found in biological systems: carbohydrates, amino acids, proteins and peptides, and nucleic acids. Working through this course, students are expected to apply their knowledge to problem-solve, deduce structures, and synthesize simple organic molecules using the studied reactions. Relationships between organic chemistry and other disciplines are noted.

CHEM 2225 is the laboratory companion to this course.


After successfully completing this course students will be able to:

  • Define aromaticity and predict its occurrence.
  • Discuss the mechanism of electrophilic substitution.
  • Predict, giving reasons, the direction of substitution on the benzene ring.
  • Predict probable products from reactions of benzene, phenols, amines, carboxylic acids, and their derivatives (aldehydes, ketones, and so on).
  • Explain the physical properties of benzene, phenols, amines, carboxylic acids, and their derivatives (aldehydes, ketones, and so on).
  • Use carbanions and enolate ions in a variety of syntheses.
  • Determine the structure of unknown organic compounds from sequences of reaction (railroad problems).
  • Identify and describe structures of amino acids, peptides, and nucleoproteins.
  • Identify and describe different carbohydrate structures.

Course outline

  • Unit 1 Aromatic Compounds
  • Unit 2 Aldehydes and Ketones
  • Unit 3 Carboxylic Acids and Their Derivatives
  • Unit 4 Organic Nitrogen Compounds
  • Unit 5 Reactions of Enolate Ions
  • Unit 6 Carbohydrates

Required text and materials

This is a companion course to CHEM 2123. Therefore, the materials package for this course will not include any materials that were required in CHEM 2123. If students did not take CHEM 2123 and do not already own the required materials, please purchase them by contacting Enrolment Services at or 1.800.663.9711 (toll-free in Canada), 250.852.7000 (Kamloops, BC), and 1.250.852.7000 (International).

Vollhardt, P., & Schore, N. (2018). Organic Chemistry: Structure and Function, loose leaf (8th ed.). New York: W. H. Freeman.
Type: Textbook: ISBN: 978-1-319-17697-6.

Schore, N. (2018). Study Guide and Solutions Manual for Organic Chemistry: Structure and Function (8th ed.). New York: W. H. Freeman.
Type: Textbook: ISBN: 978-1-319-19574-8.


Please be aware that due to COVID-19 safety guidelines all in-person exams have been suspended. As such, all final exams are currently being delivered through ProctorU, which has an approximate fee of $35 involved. There will be more information in your course shell, on how to apply, if your course has a final exam.

To successfully complete this course, students must achieve a passing grade of 50% or higher on the overall course, and 50% or higher on the final mandatory exam.

Assignment 1 10%
Assignment 2 10%
Assignment 3 10%
Assignment 4 10%
Assignment 5 10%
Final Exam* 50%


Open Learning Faculty Member

An Open Learning Faculty member is available to assist students. Primary communication through the Learning Environment’s “Mail” tool or by phone. Students will receive the necessary contact information at the start of the course.

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