The goal of this course is to present the theory of clinical anesthesia to Anesthesia Assistant
program students. Students build upon their general knowledge of pharmacological principles and
learn pharmacology in the context of clinical anesthesia. General, sedation, and regional
anesthesia is considered. Students explore pharmacological agents and their use in:
pre-anesthetic care, induction, maintenance, emergence, and recovery from general anesthesia.
Students will become familiar with the indications/contraindications, mechanism of action,
effects, and application of the most common drug categories used in anesthesia. The application
of anesthetic workstation and other technology used in the delivery of anesthesia is considered
as this course builds upon the theories from ANES 4001: Anesthesia Equipment and ANES
4011: Hemodynamic and Physiologic Monitoring.
After completing this course, students will be able to:
- Describe the basic pharmacological principles, anatomy, and physiology of the autonomic
- Discuss pharmacokinetics and characteristics of inhalational anesthetics. Define diffusion
hypoxia and factors that alter inhalational agents.
- Describe the pharmacokinetics and characteristics of barbiturates, non-barbiturates,
benzodiazepines and their reversals.
- Explain the pharmacology and use for opioids, non-opioids, and their reversals.
- Evaluate the goals of pain management appropriate to patient needs.
- Explain the pharmacology and use for muscle relaxants and their reversals. Be able to
differentiate significance of depolarizing/non-depolarizing.
- Explain the pharmacological mechanisms of induction and emergence in general anesthesia.
- Identify blood, coagulation treatments, and fluid therapy for specific situations/conditions,
and consider management plans for when complications arise.
- Describe local anesthetics in terms of mechanism of action, pharmacological effects,
indications/ contraindications, dosage and volume.
- Describe pharmacological agents that can be used alongside local anesthetics, their effects
- Describe hypotensive agents and antiarrhythmic agents.
- Describe indications/contraindications of commonly used antibiotics in the operating room.
- Module 1: Basic Pharmacological Principles
- Module 2: Review of Autonomic Nervous System
- Module 3: Inhalational Anesthetics
- Module 4: IV Anesthetics
- Module 5: Opioids and Analgesia
- Module 6: Neuromuscular Blockades
- Module 7: Blood and Fluid Therapy
- Module 8: Regional and Neuraxial Anesthetic Agents
- Module 9: Pharmacological Adjuncts
Required text and materials
This is a companion course to ANES 4011, therefore, the Butterworth 6e textbook listed below
would have been provided in ANES 4011 and is not included in this course package. If students did
not take ANES 4011 and do not already own this textbook, please be aware that students will need
to purchase it. To do so, contact firstname.lastname@example.org or phone 1.800.663.9711 (toll free in Canada) or
250.852.7000 (local & international).
- Butterworth, J., Mackey, D., & Wasnick, J. (2018). Morgan & Mikhail’s Clinical
Anesthesiology (6th ed). McGraw-Hill, Lange.
Type: Textbook: ISBN: 978-1-259-83442-4
Please be aware that due to COVID-19 safety guidelines all in-person exams have been suspended. As such, all final exams are currently being delivered through ProctorU, which has an approximate fee of $35 involved. There will be more information in your course shell, on how to apply, if your course has a final exam.
To successfully complete this course, students must achieve a passing grade of 50% or higher on
the overall course, and 50% or higher on the final mandatory exam.
Students who do not submit an assignment will be assigned a mark of zero (0) for that
assignment. It is recommended that students complete all assignments in order to achieve the
learning outcomes of the course. Students applying this course towards any TRU Health Care
program may be required to obtain a minimum grade of 60 % on the course overall to meet program
|Quiz 1: Basic Pharmacological Principles
|Assignment 1: Drug Monograph (Group Assignment)
|Assignment 2: Blood and Fluid Therapy
|Assignment 3: Recovery and Pain Management
|Discussions 1-3 (completion)
|Final Exam (mandatory)
Open Learning Faculty Member
An Open Learning Faculty Member is available to assist students. Primary communication is
through the Learning Management's "Mail" tool or by phone. Students will receive the necessary
contact information when starting the course.